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LONDON: Viagra (Sildenafil Citrate), a popular erectile dysfunction treatment known as PDE5 inhibitors, has been linked to a heightened risk of heart attacks, strokes and serious blood clots, the U. S. Food and Drug Administration (FDA) said Tuesday.
The report by the American Society for Health System Pharmacists found an increased risk of heart attacks and strokes with sildenafil citrate use, which is marketed under the brand name Viagra, and is also associated with an increased risk of serious blood clots, the agency said in a statement.
The FDA also said that it has determined that the increased risk of heart attacks, strokes and other blood clots is not consistent with the increased risk of heart attacks associated with the use of PDE5 inhibitors, the agency said.
The report was released last week following a report by the National Institutes of Health, which has been examining sildenafil citrate for more than a decade.
According to the report, the increased risk of heart attacks, strokes and serious blood clots is consistent with the increased risk of heart attacks associated with the use of PDE5 inhibitors, which is the group of drugs that includes sildenafil, an inhibitor of the PDE5 enzyme.
The FDA noted that sildenafil is the active ingredient in Viagra. It was also indicated for treating pulmonary arterial hypertension.
The report said the increased risk of heart attacks, strokes and serious blood clots may indicate a more serious problem.
"Our findings support the conclusion that PDE5 inhibitors have a greater risk of increased heart attacks, strokes and serious blood clots than reported to date," the agency said in a statement.
Sildenafil, a generic medication used to treat erectile dysfunction, is sold under the brand name Viagra. Pfizer Inc. said Tuesday that it has received regulatory approval from the U. Food and Drug Administration (FDA) for sildenafil citrate, marketed under the brand name Revatio, and has completed phase III clinical trials of sildenafil, the first oral drug to treat erectile dysfunction.
It is the first of a new class of drugs to be approved for treating erectile dysfunction, the agency said in a statement.
The report also noted that the FDA has not recommended sildenafil citrate for the treatment of pulmonary arterial hypertension, a type of high blood pressure.
Sildenafil is available only by prescription.
The report was released on Tuesday by the company that owns Viagra, which is sold under the brand name Cialis.
According to the, a study by researchers at the University of California at San Francisco found that people taking sildenafil at higher doses had a 50% lower risk of death from any cause when compared to people who were not taking the drug.
The FDA said that the findings were "well within theguidelinesfor use in patients with mild to moderate heart disease and should be used with caution," the agency's statement said.
The FDA has advised patients to consult with their healthcare provider before taking sildenafil. Viagra is also not approved for use in women.
The report noted that the drug is also indicated for treating pulmonary arterial hypertension, a type of high blood pressure.
The FDA said that the risk of cardiovascular disease for people taking sildenafil is increased when compared to patients who were not taking the drug. The increased risk of cardiovascular disease is "generally considered an indication for caution," the agency's warning said.
The study also noted that patients with diabetes, high blood pressure and other diseases of the blood vessels, including atherosclerosis, should exercise caution when taking sildenafil, the FDA said.
Viagra is also not approved for treating pulmonary arterial hypertension, a type of high blood pressure.
The FDA also noted that sildenafil was not recommended for the treatment of erectile dysfunction, although it is effective at treating other conditions, including impotence.
Cialis, the branded version of the drug, is available in a generic form.
Viagra Connect is available in Ireland for erectile dysfunction treatment which does not require a prescription. The first of its kind, Viagra Connect is a safe and discreet over-the-counter medication that can legally be bought online or over the counter in your pharmacy, without a trip to your doctor.
We need to ensure that this medicine is suitable for the person it is intended for. Therefore, it should only be purchased by the person taking it.
You can select your convenient store to collect your product and fill in the online form required.APharmacist will contact you to let you know your product is ready for collection, or you can buy onlineand complete the questions included.
When purchased online, a pharmacist will contact you by phone if they have any further questions and to advise you on the safe use of this medicine. If they are unable to speak to you when required your order may be delayed or the pharmacy medicine part of your order cancelled.
Please ensure your contact details are correct before ordering this medicine.Suitable for
Viagra Connect is for men 18 years and older who have difficulty getting and/or keeping an erection hard enough for sex
Age RestrictionYou must be at least 18 years old to purchase this product.
Directions for use:
Please read the enclosed leaflet carefully before use.
• take 1 tablet approximately one hour before sexual activity• swallow tablet whole with water• do not take more than 1 tablet a dayViagra Connect starts to work within 30-60 minutes. You may take it up to 4 hours before sexual activity.
Hazards and Cautions
Do NOT take if you:
Talk to your pharmacist or doctor before taking if you:
=Viagra Connect is a free online pharmacist service based in the UK that provides patients with a safe and convenient way to buy Viagra and other generic prescription medications online. If you are wants with an erection problems can be treated there is no side effects andazuredirect_ collaborated_at_https%!4!95%!0!95
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IMPORTANT NOTICE: Please be aware, prior to sale, you are advised to have a short phone call consultation with our Pharmacist. Automatic purchase consents the Pharmacist to give you a quick call.
Viagra Connect is available without a Prescription but requires a brief consultation with the Pharmacist. It is available in a 4 pack or an 8 pack. Viagra Connect contains Sildenafil 50mg which works by relaxing the penis blood vessels, allowing blood to flow when you get aroused causing erections and potency. Viagra Connect will only help men become erect if you are aroused. Only for adult use, men 18 years plus.
How to be taken:
VIAGRA CONNECT is not to be taken if:
Please read instructions carefully provided.
Viagra Connect is a fast acting drug for erectile dysfunction which can last up to 4 hours and takes effect within 30 minutes after administration.
Sildenafil Citrate 50 mg Tablets: This tablet is specifically formulated to treat the symptoms of erectile disfunction and is highly effective in treating it, the most common sexual disorder affecting men over the age of 40 years. Provides a solution to erectile dysfunction in men who suffer from impotence due to conditions such as heart disease or diabetes, or who have problems with their physical or mental health.
Viagra Connect ensures fast and effective results that last as long as 36 hours and come without side effects. It works by relaxing the blood vessels in the penis, allowing blood to flow into the phallus when you get sexually excited and causing the desired stiffness.
IMPORTANT NOTICE: You are advised to have a short phone call consultation with our Pharmacist during the licencing of your order. Automatic purchase consents the Pharmacist to a quick call with a trusted party person. A brief consultation with the Pharmacist the call are recommended to get a quick appointment.Who should not take Viagra Connect:
Stade de France Pharmacy